Nobody is arguing against basic safety regulations. But regulation goes far beyond basic safety, and sometimes becomes un-safety (when, for instance, the feds say I can have a defogger, but not a true defroster, for my windshield--move the DoD to International Falls, Minn.). And sometimes it is captured by special interests, as with the EPA and the WOTUS rule that would have let them regulate puddles in your yard. Look up the Sackett case. It reached SCOTUS and one of the most liberal justces said, "I can't believe this is happening in the US." He said that to the EPA's lawyer.
The government lost, 9-0.
Or take the so-called renewable fuel standard, that puts 1/3 of America's corn crop into our gas tanks, lowering mileage to no improvement in air quality. (Oxygenates were introduced into the gasoline supply to fool engine controls into running a bit richer, but cars from the past five or ten years aren't affected and don't need it.) This drives up food prices for everyone, which hurts the poor most of all, and especially hurts the people of Mexico, who get most of their from the US. When the ethanol mandate was extended and expanded, Mexico complained--and I think they had a good point.
Alexis de Toqueville noted that in his day the US didn't need pyblic assistance because private 'charity' took care of things. But the government has helped to drive most of those organizations out of that businesd. Not self-dependence. Not community aid. Government dependence.