3,801

(29 replies, posted in TheNextBigWriter Premium)

Karin et al, thanks for the additional info. I'll start hunting where you suggest.

Following is the part I'm most unclear about. Let's say that most men and women are innoculated via gene therapy against a highly contagious and fatal disease. Everything seems fine. People go back to their normal lives and start having babies who are now probably carriers of the modified gene by inheriting it from their parents. Those children have babies, etc.

How might the modified gene eventually cause sterility or defective babies several generations beyond the original innoculation? I understand the basics of DNA from the parents combining after conception, but not how such a defect would creep in after a few generations.

Thanks.
Dirk

Sol, one of my new readers made a copy of my second draft to read offline because he didn't think he could finish it during the one week trial period. Currently, what happens when the trial is over? Will the reader still be able to read and leave reviews? I want his input, but don't want to have to track a bunch of offline reviews on top of regular and inline reviews if I can help it.

Thanks.
Dirk

3,803

(29 replies, posted in TheNextBigWriter Premium)

Now to put this baby on steroids!

As mentioned in my earlier post, genetic engineering of humans will be banned some time in the next few hundred years because of too many unintended side effects, including Apollo's incurable Trembler's disease. I was hoping to make the cause for the ban huge, big enough to scare the human race from ever resuming engineering on humans.

Specifically, I've always wondered if it was possible to genetically engineer ourselves into sterility that doesn't show for a few generations. Billions of people potentially becoming evolutionary dead ends. Probably the result of providing resistance against an ebola-like worldwide epidemic. The unintended consequence would be a great reason for a universal ban. They'll call it God's Law (i.e., don't mess with creation).

Can anyone envision a scenario as to how that might work?

Thanks.
Dirk

3,804

(29 replies, posted in TheNextBigWriter Premium)

I found a really simple example that demonstrated the Principle of Parsimony for evolution. I knew about Occam's razor, but it never occured to me that it applied so well to the construction of evolutionary trees. Cool. Thank you, NJC.

3,805

(29 replies, posted in TheNextBigWriter Premium)

That's a cool quote.

Mike, I just want more than "It's a mental illness and there is no cure." I'm hoping to make it a genetic change that can't be altered because, as NJC, suggested, the change would be incompatible with the human body in that future era because of too much tinkering.

I'll probably include a galaxy-wide ban on genetic engineering, enacted some time in the 22nd or 23rd century after too many severe side-effects come to light that can't be undone. Apollo's illness will just be one more resulting illness. A ban on genetic engineering will explain why humans in 4017 aren't genetically-engineered supermen, which seems to be where we're headed.

Thanks to all. I'll follow up on some of the posts to this thread.

3,806

(2 replies, posted in Science Fiction, Steampunk, and Space Opera)

Max, how far back does the car need to bounce? If it's a few inches, just go with it. I'm probably totally wrong on the physics here (usually am), but if the car is going from 40 mph to zero, wouldn't the rear of the car lift at least a little off the ground for a moment? If so, then it can drop down and bounce backward, especially if it's on a hill.

Dirk

3,807

(10 replies, posted in Writing Tips & Site Help)

Amy, tsk, tsk. Shouldn't you be writing?

I'm still considering Swarm as the Realm's roaming equivalent of the Praetorian Fleet.

Besides that, I want it very simple. I'll either go with Fleet/fleet or Fleet/force to distinguish the whole fleet from a subset of the fleet. Hopefully, I won't find it necessary to name battle groups.

Most readers probably won't give a damn about Fleet/fleet, but it eases my OCD. :-)

Gracias to all.
Dirk

3,808

(29 replies, posted in TheNextBigWriter Premium)

Thank you, Karin.

3,809

(29 replies, posted in TheNextBigWriter Premium)

Nice! So there is a potential cascade effect.
Good to know.

Thanks
Dirk

3,810

(29 replies, posted in TheNextBigWriter Premium)

The disease manifests as noted above, resulting in visible trembling, which can be taken as a sign of mental illness. Apollo comes from a long line of psychopathic emperors who routinely overthrow each other using the family motto for cover: Only the mentally fit shall rule! Apollo has a half-brother who wants the throne but is not in the direct line of succession, so he's looking for an excuse to move against Apollo.

There are many ways I could represent this, including a disease that's not well understood but is believed to be the result of long-term genetic engineering. With that sentence alone, I'm halfway home. I could stop there, but I'd like to throw in a little genetic depth, on the order of a paragraph.

For example, if the illness is the result of genetic engineering that modified a single gene who's only other known purpose is to, say, improve night vision, then you stop messing with that gene in humans, and the illness goes away. If, however, the gene change(s) provide the only known defense against the "Ebola" of the fifth millenium, then there is no alternative. Again, I could stop there.

However, I'd like to make it so fundamental to genetically-engineered humans that there is no way to change the gene(s) in question without a cascade of deadly effects from other, dependent genes that have also been messed with. Essentially, is it possible to construct a house of cards from which there is no realistic hope of return?

My second question I can probably research on my own, which is how is gene therapy able to alter all copies of a defective gene in a body with trillions of cells that are constantly dividing?

Ideas?
Dirk

3,811

(29 replies, posted in TheNextBigWriter Premium)

The character, Apollo, experiences tremors in his left hand and forearm, especially when he is under stress. Tentatively, it's called Trembler's disease. There's no known cure and the only way to control it is with narcotics. By the time the story gets rolling, Apollo is already an addict.

The mental disease plays into a larger theme in the story about Apollo and his cousin, Joseph, both secretly hearing the voice of God, their reactions to him, and the consequences for the galaxy.

3,812

(29 replies, posted in TheNextBigWriter Premium)

Thanks, dagnee. I'll wait to see if anyone on the site has any knowledge on the subject and then contact DiSalvo with (hopefully) intelligent questions.

I do plan to keep the mental illness a secret from most of the character's family and the galaxy at large, as I do currently. However, my previous attempt at this fell apart after several chapters. I'm hoping to avoid that in my next draft.

Thanks for the lead.
Dirk

3,813

(29 replies, posted in TheNextBigWriter Premium)

Hi.

I'm trying to create a mental disease that strikes one of my characters in a sci-fi future set in 4017. I was hoping to make the disease a side-effect of genetic engineering that cannot be undone.

1. Is it possible to tinker with our DNA to such an extent that the side-effect becomes essentially permanent (e.g., a series of interdependent gene changes that are too complex to unravel just the gene causing the mental disease, without also causing a cascade of other, more serious side-effects)?

OR

2. Can I make it simple, such as making genetic changes to fight off a fatal disease, which results in the mental disease as a side-effect?

Thanks.
Dirk

amy s wrote:

I think there are two kinds of funny bones. Ex- those who get Seinfeld and those who don't. I am one of those who don't.

And no, I didn't google. I was laughing too hard.

I could never get into Seinfeld. Ditto for Everybody Loves Raymond. However, for years I thought Married With Children was too crude. I'd watch a few minutes here and there while channel surfing. Eventually, I watched whole episodes and soon thought it was a riot. I've since seen every episode.

There are two answers:
a) I have more named entities in my spreadsheet than I will probably ever use. For example, I have ten classes of warships, ten classes of weapons, etc., but I ony sprinkle some of those names in here and there to add a little realism. So far, I've only ever mentioned one ship class by name in the book. Similarly I have ship names (only three in book one), and ship types that are easy to understand (e.g., starfighter, troop carrier, civilian transport, etc.).
b) I remind the reader what the named entity is. For example, rather than saying Dawn, I refer to it as the planet Dawn or the rebel planet, etc. Similarly, rather than saying General Equitius, I say General Equitius, the Imperial physician. In my case, it's especially important because those planets and characters generally only appear once every two chapters (I alternate back and forth between two interwoven stories.

Okay, fess up. You both googled it, didn't you?

One of my favorite surprises while writing my space opera is when I realize that I can use an experience out of my own life, put it on steroids, and insert it into the story. Happens over and over.

3,818

(16 replies, posted in The Aurora Mission)

mikira (AKA KLSundstrom) wrote:

Dirk, I love your epigraphs, I suggest leaving some of the quotes as the ones you have already.

Thanks, Karen. I'm only going to replace the "real-world" quotes (e.g., the JFK quote in chapter 3). The epigraphs that you liked in chapters 1 & 2 are the style I'll be going for when I eventually rewrite Acts I & 2. Act III already uses my newer style of quotes. As you'll eventually see, I often use them for something tongue-in-cheek, since the book isn't meant to be too serious.

Dirk

njc wrote:

Ontology recapitulates phylonogy.
Every finite dimensional inner product field has an orthonormal basis.
The divergence of the curl is a zero field.
And ... the proper uses of commas and semicolons.

I plugged those four sentences into Google for the hell of it. I got porn.

I read a review of Scrivener not too long ago. The reviewer said one of its biggest drawbacks is the difficulty importing from MS Word. So, if you work with an editor and use track changes and MS Word comments to go back and forth like I do, you'll end up doing a lot of cutting and pasting to get it back in, which also means you can forget about track changes and comments. If it wasn't for that critical limitation I might have bought it.

Instead, I write using MS Word, where I've configured the grammar checker to my taste, and the document map that works with my chapter headings. The document map (available on the View tab/ribbon) is great because it lists all of my chapters; with a single click, I can jump to any chapter I want.

Like penang, I use a spreadsheet to keep track of every named item I have in my story (stars, planets, ships, characters, military ranks, etc.). I also have a Word document for my story and chapter outlines, and another one for research information and a long list of to dos. I should probably split the last file in two.

I've gotten through almost two drafts that way with minimal overhead or fuss.

Dirk

NJC, I recognize a 9-volt Energizer battery in your pictures. If I put that on my tongue it hurts. Besides that, is there anything else I need to know for tomorrow's exam? :-)

Dirk

njc wrote:

So ... what is it?  I'll bury the answer in the next post.  Have fun thinking it over.  I think you'll get a little kick out of it.

Amy, make him stop. :-)

amy s wrote:

Did I answer that sufficiently?

Thanks, Amy. I have a better understanding, but far from perfect. I find it very complex, even without the concept of the matrix. Why did you go with something so hard to understand? For example, mages draw power from the ground with their staffs into their reserve in order to cast spells. Yet, new mages have to ground in order to keep their overloaded reserve from blowing them up. These seem contradictory to me. The first case draws power, while the other sends it back, both by grounding.

I doubt you can simplify it at this point without a major rewrite of the books, but I look forward to reading the first book, which I accidentally skipped, to see how much I understand your explanation there.

Thanks.
Dirk

njc wrote:

The motor of your mixer is probably a universal motor, which uses 'brushes', blocks of graphite which carry current into a surface sliding beneath them.  In the case of the universal motor, the sliding contacts are a split ring, creating a commutator, which connects the windings differently according to how the rotor is turned.

The motor of the air conditioner is almost certainly a brushless induction motor which requires AC.  The motor is completely immersed in the air conditioner's heat-transfer 'coolant', which cools the motor and, via a little oil mixed into the fluid, also lubricates the motor.

I beg to differ, njc. I don't think the Filbert Flange will mesh with the Grapple Grommet.
https://www.youtube.com/watch?v=FJ6jCM3UeZo

You're talking to a guy who's knowledge of electricity is limited to getting zapped by a handmixer and melting a screwdriver. That's probably true of your target audience, too. I had to read your explanation several times just to figure out what questions to ask:

So casting always comes from the reserve? You're not simply routing power from the ground directly at the target (which would be a much easier explanation, BTW)? You have to absorb it into your reserve first? Yes?

If any of that is correct (doubtful), why then do new mages need to learn how to ground quickly to avoid blowing up? If their reserve is limited, why doesn't that simply limit the amount of power they can wield? I'm missing something. I thought the ground (earth) is where the power comes from.

Aside from that, is matrix the same as reserve?

How should I visualize the matrix? When you say reserve, by default, I visualize a star-like place in the chest or mind that glows brighter/hotter (for those who can see it) as the reserve builds. Or power that makes their entire bodies glow brighter/hotter (again, for those who can see it) as the reserve builds.

I'm going to pass on the explanation about Alina and Katerin. She's now a mage, the same as exeryone else, which I understand. Let's leave it at that. :-)